James Cook University
QLD Australia
Prof Alan Nimmo is currently Professor of Medical Science in the College of Medicine and Dentistry at James Cook University. He is originally from Edinburgh, and graduated from Edinburgh University with Honours in Pharmacology. His Honours project involved demonstrating the presence of substance P in the human brain. Much of his research over the intervening years has focused on the role substance P, and other neuropeptides play in inflammation. This has included research into asthma (Hammersmith Hospital, University of London) and urogenital disorders (School of Medicine, University of Leeds). Whilst at the University of Leeds, Alan completed his PhD. In 1992, Alan moved to Australia to take up an academic position at JCU. He remained at JCU for 13 years, before accepting a position as A/Prof in Pathology at the University of Adelaide. In 2008, Alan returned to JCU to take up the position of Prof of Medical Science.
Alan has acted as a consultant for a number of pharmaceutical companies, including Pfizer, on their programs examining inflammatory neuropeptides as novel therapeutic targets. Whilst at JCU, Alan began a productive research collaboration with Prof Robert Vink. Bob had a long-standing interest in traumatic brain injury (TBI), and together they worked on developing a novel therapy that targeted the inflammatory response and cerebral oedema associated with TBI. This led to a co-development program with Hoffmann-La Roche, and the establishment of a spin-off company to commercialise their novel TBI therapy. That treatment is currently in Phase 2 human clinical trials. More recently, Alan has developed an interest in the role inflammatory processes may play in the invasive and metastatic progression of cancer, and has developed a therapy that inhibits the growth of secondary tumours (cerebral metastases) in the brain. This work has led to the establishment of another spin-off biotechnology, CH Biotech.